Thompson & Thompson Genetics and Genomics in Medicine, 9th Edition
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Sources and Acknowledgments
1 Introduction
2 Introduction to the Human Genome
3 The Human Genome: Gene Structure and Function
4 Human Genetic Diversity: Genomic Variation
5 Principles of Clinical Cytogenomics and Genome Analysis
6 The Chromosomal and Genomic Basis of Disease: Disorders of the Autosomes and Sex Chromosomes
7 Patterns of Single-Gene Inheritance
8 Complex Inheritance of Common Multifactorial Disorders
9 Genetic Variation in Populations
10 Identifying the Genetic Basis for Human Disease
11 The Molecular Basis of Genetic Disease
12 The Molecular, Biochemical, and Cellular Basis of Genetic Disease
13 The Treatment of Genetic Disease
14 Developmental Genetics and Birth Defects
15 Cancer Genetics and Genomics
16 Risk Assessment and Genetic Counseling
17 Preconception and Prenatal Screening and Diagnosis
18 Application of Genomics to Medicine and Individualized Health Care
19 Ethical and Social Issues in Genetics and Genomics
Epigenetics
Cases: Clinical Case Studies Illustrating Genetic Principles
Glossary
Answers to Problems
Index
1 Introduction
2 Introduction to the Human Genome
3 The Human Genome: Gene Structure and Function
4 Human Genetic Diversity: Genomic Variation
5 Principles of Clinical Cytogenomics and Genome Analysis
6 The Chromosomal and Genomic Basis of Disease: Disorders of the Autosomes and Sex Chromosomes
7 Patterns of Single-Gene Inheritance
8 Complex Inheritance of Common Multifactorial Disorders
9 Genetic Variation in Populations
10 Identifying the Genetic Basis for Human Disease
11 The Molecular Basis of Genetic Disease
12 The Molecular, Biochemical, and Cellular Basis of Genetic Disease
13 The Treatment of Genetic Disease
14 Developmental Genetics and Birth Defects
15 Cancer Genetics and Genomics
16 Risk Assessment and Genetic Counseling
17 Preconception and Prenatal Screening and Diagnosis
18 Application of Genomics to Medicine and Individualized Health Care
19 Ethical and Social Issues in Genetics and Genomics
Epigenetics
Cases: Clinical Case Studies Illustrating Genetic Principles
Glossary
Answers to Problems
Index
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